Group
Second-generation antihistamine (H1 receptor antagonist)
Mechanism of Action
Blocks peripheral H1 histamine receptors and inhibits platelet-activating factor (PAF), reducing allergic symptoms and inflammation.
Indications
- Allergic rhinitis (seasonal and perennial)
- Chronic urticaria (hives)
- Other allergic conditions as prescribed
Dose
- Adults and children ≥12 years: 10 mg orally once daily.
- Children 6–11 years: 5 mg orally once daily.
Major Side Effects
- Headache
- Drowsiness (less than first-generation antihistamines)
- Fatigue
- Mild gastrointestinal upset (nausea, dry mouth)
- Rare: palpitations, dizziness
Contraindications
- Hypersensitivity to rupatadine or any component of the formulation
- Severe hepatic impairment
Compatible Fluid
Oral tablets – swallow with water; no IV formulation.
Type of Administration
Once-daily oral therapy for allergic conditions and chronic urticaria.